Cardamom and Dental Health: Natural Support Against Inflammation - Zum Heilen: One Health

Natural Oral Health and Inflammation Support

Cardamom for Dental Health

Cardamom’s natural antimicrobial and anti-inflammatory properties help support gum health, freshen breath, and reduce inflammation, offering a natural path to better oral wellness.

Overview

Cardamom exhibits strong antibacterial activity against major oral pathogens like Streptococcus mutans, Porphyromonas gingivalis, and Prevotella intermedia, effectively disrupting biofilms and bacterial membranes at low concentrations.

Its anti-inflammatory properties, coupled with demonstrated safety and efficacy in mouthwash and oral care formulations, make cardamom a promising natural agent for maintaining oral health and preventing periodontal disease.

Research & Publications

The Antifungal Potential of Cardamom-based Denteez Mouthwash Against Opportunistic Fungal Infections in the Oral Cavity

Tharakan M, Kugaji M, Bhat K, Varkey P, Joshi M, Nanda B. <> Journal of Advanced Oral Research. 2023;14(2):169-176. doi:10.1177/23202068231194895

This study evaluated the antifungal activity of Denteez™ mouthwash, a cardamom-based herbal formulation, against multiple Candida species causing oral candidiasis. It was tested on five standard Candida species and 54 clinical isolates, many of which showed resistance to commonly used antifungal drugs like fluconazole. Denteez™ demonstrated strong antifungal activity, inhibiting 98.2% of the isolates with a MIC of 1.25% and showed time-dependent fungal suppression. These findings suggest that Denteez™ may serve as an effective herbal alternative in managing oral candidiasis, especially in cases with rising drug resistance.

Antibacterial, Anti-inflammatory properties and Therapeutic Benefits of Cardamom (Elettaria cardamomum)

Dilshad, K. (2024). INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT. https://doi.org/10.55041/ijsrem30881.

This study demonstrates that both fruit and seed extracts of Elettaria cardamomum, rich in volatile compounds, possess potent antibacterial activity against key periodontal pathogens such as P. gingivalis, F. nucleatum, and A. actinomycetemcomitans, with low MIC and MBC values. The extracts disrupted bacterial cell membranes, inhibited biofilm formation, and significantly reduced pro-inflammatory cytokines (IL-1β, TNF-α, IL-8) in macrophages stimulated with lipopolysaccharide. The anti-inflammatory effects were linked to the inhibition of the NF-κB signaling pathway. These findings support the potential of cardamom extracts as natural therapeutic agents for managing periodontal infections.

The Role of Cardamom Oil in Oral Health: A Short Review

Jesylne, P., Soundarajan, S., Murthykumar, K., & Meenakshi, M. (2016). Research Journal of Pharmacy and Technology, 9, 272-274. https://doi.org/10.5958/0974-360X.2016.00050.0.

This study highlights the broad medicinal potential of cardamom, a spice native to southern India, beyond its traditional culinary use. It emphasizes cardamom’s ability to regulate inflammatory and immune responses, suggesting a possible role in cancer prevention. The research also demonstrates the antimicrobial effects of cardamom extracts against common oral pathogens such as Streptococcus mutans and Candida albicans.

Evaluation of Antibacterial Effect of Aqueous-Alcoholic Elettaria Cardamomum Herbal Extract on Aggregatibacter Actinomycetemcomitans.

Nouri, ZohrehTabibzadeh & Ismaili, FatemehSadat & Yadegari, Zahra & Karimi, Mehrdad & Asghari, Alireza. (2023). Journal of Interdisciplinary Dentistry. 13. 61. 10.4103/jid.jid_14_22.

This study evaluated the antimicrobial effect of hydroalcoholic extract of Elettaria cardamomum against Aggregatibacter actinomycetemcomitans (Aa), a key pathogen in periodontitis. Using agar-well diffusion and broth microdilution methods, the extract showed clear antibacterial activity with inhibition zones of 20.0–20.5 mm at 25% and 50% concentrations. The MIC and MBC values were 0.0039 mg/ml, indicating potent efficacy, though slightly less than chlorhexidine. The findings suggest that cardamom extract could be a promising natural alternative to chlorhexidine in oral care formulations.

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